{
    "name": "Creatinine Clearance Calculator (Cockcroft–Gault)",
    "url": "https://calculators.geekmidst.com/calculators/creatinine-clearance-estimate-calculator",
    "markdown": "https://calculators.geekmidst.com/calculators/creatinine-clearance-estimate-calculator.md",
    "category": "Healthcare operations",
    "description": "Estimate creatinine clearance in mL/min with the Cockcroft–Gault equation from age, sex, weight and serum creatinine in mg/dL or µmol/L, for professional use.",
    "summary": "Cockcroft–Gault estimates creatinine clearance as (140 − age) × weight ÷ (72 × serum creatinine), × 0.85 for women. It supports, and does not replace, clinical judgement.",
    "also_called": [
        "CrCl calculator",
        "Cockcroft–Gault calculator"
    ],
    "applies_to": "Worldwide",
    "last_updated": "2026-10-29",
    "computation": "Results are computed in the visitor’s browser on the HTML page. This API describes the calculator; it does not compute results.",
    "inputs": [
        {
            "name": "age",
            "label": "Age",
            "type": "number",
            "default": "60",
            "unit": "years"
        },
        {
            "name": "sex",
            "label": "Sex",
            "type": "segmented",
            "default": "male",
            "options": {
                "male": "Male",
                "female": "Female"
            }
        },
        {
            "name": "weight",
            "label": "Weight",
            "type": "number",
            "default": "72"
        },
        {
            "name": "weight_unit",
            "label": "Weight in",
            "type": "segmented",
            "default": "kg",
            "options": {
                "kg": "kg",
                "lb": "lb"
            }
        },
        {
            "name": "creatinine",
            "label": "Serum creatinine",
            "type": "number",
            "default": "1.0"
        },
        {
            "name": "creatinine_unit",
            "label": "Creatinine in",
            "type": "segmented",
            "default": "mg_dl",
            "options": {
                "mg_dl": "mg/dL",
                "umol_l": "µmol/L"
            }
        }
    ],
    "outputs": [
        {
            "key": "crcl",
            "label": "Estimated creatinine clearance",
            "format": "number"
        },
        {
            "key": "crcl_ml_s",
            "label": "Creatinine clearance",
            "format": "number"
        },
        {
            "key": "weight_kg",
            "label": "Weight used",
            "format": "number"
        },
        {
            "key": "creatinine_mg_dl",
            "label": "Creatinine used",
            "format": "number"
        }
    ],
    "formula": {
        "text": "CrCl (mL/min) = (140 − Age) × Weight (kg) ÷ (72 × SCr in mg/dL), × 0.85 if female;  SCr mg/dL = µmol/L ÷ 88.4",
        "variables": {
            "Age": "years (adults)",
            "Weight": "kg (1 lb = 0.45359237 kg)",
            "SCr": "serum creatinine at steady state"
        }
    },
    "worked_example": {
        "inputs": {
            "age": "60",
            "sex": "male",
            "weight": "72",
            "weight_unit": "kg",
            "creatinine": "1.0",
            "creatinine_unit": "mg_dl"
        },
        "steps": [
            "(140 − 60) × 72 = 5,760.",
            "72 × 1.0 = 72.",
            "5,760 ÷ 72 = 80 mL/min (male, so no 0.85 factor); 80 ÷ 60 = 1.33 mL/s."
        ],
        "result": "A 60-year-old man weighing 72 kg with a serum creatinine of 1.0 mg/dL has an estimated creatinine clearance of 80 mL/min."
    },
    "interpretation": "Cockcroft–Gault creatinine clearance is the measure many drug labels use for renal dose adjustment. For staging chronic kidney disease, laboratories report an eGFR (for example CKD-EPI 2021) instead, which is not interchangeable.",
    "assumptions": [
        "Serum creatinine is stable (not in acute kidney injury).",
        "The weight entered is the one your protocol or the drug label specifies."
    ],
    "limitations": [
        "Derived in adults in 1976; less accurate at extremes of age, weight or muscle mass, in pregnancy and in unstable kidney function.",
        "Creatinine assays have changed since the equation was developed, which can raise estimates slightly."
    ],
    "rules": null,
    "faqs": [
        {
            "question": "Which weight should I use?",
            "answer": "The original study used actual body weight. In obesity, many protocols use ideal or adjusted body weight; follow the drug label or your local guideline."
        },
        {
            "question": "How is this different from eGFR?",
            "answer": "eGFR equations estimate glomerular filtration indexed to 1.73 m² of body surface area. Cockcroft–Gault estimates unindexed creatinine clearance in mL/min, the basis of many drug-dosing tables."
        }
    ],
    "sources": [
        {
            "title": "WikEM: Creatinine clearance (Cockcroft DW, Gault MH, Nephron 1976;16:31–41)",
            "url": "https://wikem.org/wiki/Creatinine_clearance_calculator"
        }
    ],
    "related": [
        {
            "name": "GFR Calculator",
            "url": "https://calculators.geekmidst.com/calculators/gfr-calculator"
        },
        {
            "name": "Body Surface Area Calculator",
            "url": "https://calculators.geekmidst.com/calculators/body-surface-area-calculator"
        },
        {
            "name": "Anion Gap Calculator",
            "url": "https://calculators.geekmidst.com/calculators/anion-gap-calculator"
        },
        {
            "name": "Corrected Calcium Calculator",
            "url": "https://calculators.geekmidst.com/calculators/corrected-calcium-calculator"
        }
    ],
    "disclaimer": "This is a general screening estimate for adults, not medical advice or a diagnosis. Talk to a qualified health professional about your health.",
    "publisher": "GM¹X CalcVerse"
}